Back to all supplements

    Whey Protein

    Whey protein is a complete protein isolated from the liquid byproduct of cheese manufacturing. It provides all nine essential amino acids in high bioavailable concentrations and is digested rapidly, making it one of the most widely studied and utilized protein supplements for athletic performance and general health.

    Research Evidence
    Increases muscle protein synthesis and supports lean mass gains when combined with resistance training
    Strong
    Supports body composition improvements including fat loss during caloric restriction
    Moderate
    May enhance bone mineral density through improved calcium absorption and IGF-1 signaling
    Moderate
    Improves post-exercise recovery and reduces markers of muscle damage
    Strong
    Can help regulate appetite and promote satiety compared to other macronutrients
    Moderate

    Expert Evidence

    10 references from 3 experts

    Currently takes

    “The magic number appears to be 1.6 grams of protein intake per kilogram of body weight per day. Older adults should target an even higher 2 grams per kilogram. Protein powder is a fantastic option for reaching these high protein intakes.”

    9 Supplements With STRONG Evidence Of Benefit

    2:14
    Brad Stanfield

    4 references in 4 episodes from 2023–2025

    AI-generated summary

    Stanfield personally uses protein powder and recommends targeting 1.6g of protein per kilogram of body weight daily (2g/kg for older adults), noting protein powders as a practical way to hit these targets. He monitors third-party testing reports for contaminants but relies on FDA safety thresholds rather than avoiding protein powder altogether. No specific brand preference, form (whey vs. plant), or timing guidance is discussed beyond the suggestion of a low-calorie shake in the morning for calorie restriction.

    Currently takes

    “Whey protein contains relatively high amounts of the amino acid leucine and therefore is going to be the superior form of protein if your goal is to grow muscle or get stronger, to repair muscle damage caused by exercise, or simply to engage protein synthesis.”

    AMA #19: Collagen vs. Whey Protein, Creatine, Smelling Salts, Stimulants & More

    5:23
    Andrew Huberman

    3 references in 3 episodes from 2023–2025

    AI-generated summary

    Huberman personally uses whey protein routinely and considers it the superior protein source for muscle growth, strength, and repair due to its high leucine content. He advises gradually increasing dosage over several days to avoid gastric distress. No specific dosage numbers, brand preferences, or cautions beyond digestive tolerance are discussed.

    Discusses

    “They do not realize the impact protein intake has on bone health. It may enhance bone health by improving calcium absorption, increasing IGF-1, and by increasing lean body mass. It accounts for about 2 to 4% of the overall variance in bone mineral density.”

    Build Stronger Bones at Every Age

    1:28:26
    Andy Galpin

    3 references in 2 episodes

    AI-generated summary

    Galpin highlights protein's underappreciated role in bone health, citing a 2019 systematic review showing it may enhance bone mineral density by 2-4% through improved calcium absorption, increased IGF-1, and lean body mass gains. He recommends 40g of protein-dominant food under 220 calories within 30 minutes before sleep. No evidence of personal whey protein use is given, no specific whey brand or form is recommended, and no cautions are discussed.

    Safety & Cautions

    Side Effects

    • Bloating or gas
    • Digestive discomfort in lactose-sensitive individuals
    • Acne exacerbation in susceptible people
    • Possible kidney strain at excessive doses in those with pre-existing renal conditions
    Whey protein is generally well-tolerated by most people at standard doses. Those with dairy allergies or severe lactose intolerance should opt for whey isolate or consider alternative protein sources, and individuals with kidney disease should consult a physician before significantly increasing protein intake.
    Pairs Well With
    Price Comparison
    From $1.11/ct
    N
    NutricostBest Value
    4.6
    65 ct

    $1.11/ct

    $72.45 total

    N
    NOW Sports
    4.5
    25 ct

    $1.48/ct

    $36.99 total

    D
    Dymatize
    4.5
    20 ct

    $1.67/ct

    $33.43 total

    M
    Momentous
    4.2
    25 ct

    $2.40/ct

    $59.95 total

    A
    Ancient Nutrition
    4.6
    20 ct

    $2.75/ct

    $54.95 total

    F
    FlavCity
    4.3
    20 ct

    $3.00/ct

    $59.99 total

    O
    Optimum Nutrition
    4.6
    24 ct

    $3.42/ct

    $81.99 total