Ashwagandha
Evening or with last meal
Ashwagandha (Withania somnifera) is an adaptogenic herb with a long history in Ayurvedic medicine. It contains withanolides as its primary bioactive compounds and is widely studied for its effects on stress resilience, cortisol modulation, and cognitive function.
Research Evidence
Reduces perceived stress and cortisol levels
StrongBlunts physiological stress response during high-intensity exercise
ModerateImproves sleep quality in stressed individuals
ModerateSupports cognitive function under stress
ModerateMay reduce anxiety symptoms
StrongExpert Evidence
74 references from 5 experts
“I do take ashwagandha at a dosage of 300 milligrams; I take it of course in the evening and at night.”
How to Control Your Cortisol & Overcome Burnout
1:49:2831 references in 14 episodes from 2021–2025
Safety & Cautions
Side Effects
- Drowsiness or sedation
- Gastrointestinal discomfort
- Possible thyroid hormone elevation with prolonged use
- Headache in some individuals
Generally well-tolerated in clinical trials at standard doses. However, prolonged continuous use without breaks is not well studied, and individuals with thyroid conditions or those on sedative medications should consult a healthcare provider.
Pairs Well With
Price Comparison
From $0.08/ct
N
NOW FoodsBest Value
4.5
•90 ct$0.08/ct
$7.33 total
N
Nutricost
4.6
•120 ct$0.12/ct
$14.95 total
D
Double Wood
4.6
•120 ct$0.10/ct
$11.65 total
J
Jarrow Formulas
4.5
•120 ct$0.16/ct
$19.49 total