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    Choline

    With meals

    Choline is an essential nutrient that serves as a building block for cell membranes and is critical for producing the neurotransmitter acetylcholine. It is found naturally in foods like eggs, liver, fish, and soybeans, though many people fall short of adequate intake through diet alone. Choline also plays a key role in methylation processes and lipid transport.

    Research Evidence
    Helps maintain cell membrane structural integrity
    Strong
    Supports acetylcholine synthesis and cholinergic brain function
    Strong
    Contributes to healthy homocysteine metabolism via methylation
    Moderate
    May support cognitive performance and memory in older adults
    Moderate
    Essential for fetal brain development during pregnancy
    Strong
    May help preserve blood-brain barrier integrity after injury
    Limited
    Source: Examine.com

    Expert Evidence

    14 references from 4 experts

    “The other important precursor for acetylcholine is choline. This is also relatively abundant in lemon tart because egg yolk is high in choline.”

    Low-Carb Lemon Tart Dessert (High Citrate & Choline)

    7:23
    Safety & Cautions

    Side Effects

    • Fishy body odor at high doses
    • Nausea or gastrointestinal discomfort
    • Excessive sweating
    • Low blood pressure at very high intakes
    Choline is generally well-tolerated at doses within the recommended range. Very high intakes above 3,500 mg per day may cause adverse effects, and individuals with trimethylaminuria should consult a doctor before supplementing.
    Pairs Well With
    Omega-3 Fatty Acids (EPA)Alpha-GPC
    Price Comparison
    From $0.24/ct
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    Jarrow FormulasBest Value
    4.6
    •100 ct

    $0.24/ct

    $23.84 total

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