Omega-3 Fatty Acids (EPA)
Omega-3 fatty acids, primarily EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are essential polyunsaturated fats found abundantly in fatty fish like salmon, mackerel, and sardines, as well as in algae-based supplements. They are among the most extensively researched dietary supplements, with decades of evidence supporting roles in cardiovascular health, brain function, and systemic inflammation reduction.
Research Evidence
May improve symptoms of depression, particularly with higher EPA ratios
ModerateMay support metabolic rate when taken at higher doses
LimitedReduces blood triglyceride levels
StrongSupports cardiovascular health and reduces heart disease risk
StrongSupports cognitive function and brain health maintenance
ModerateReduces systemic inflammation markers
StrongExpert Evidence
261 references from 6 experts
Safety & Cautions
Side Effects
- Fishy aftertaste or burping
- Mild digestive discomfort
- Slightly increased bleeding time at high doses
- Occasional nausea
Omega-3 supplements are generally well-tolerated at standard doses. Those on blood-thinning medications should consult a physician before taking high doses, as omega-3s may have mild anticoagulant effects.
Pairs Well With
Price Comparison
From $0.07/ct
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NOW FoodsBest Value
4.7
•180 ct$0.07/ct
$13.22 total
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Nutricost
4.7
•240 ct$0.12/ct
$27.95 total
N
NatureWise
4.6
•60 ct$0.12/ct
$7.22 total
N
Nordic Naturals
4.7
•120 ct$0.20/ct
$24.44 total
C
Carlson Labs
4.7
•130 ct$0.24/ct
$31.11 total
M
MAV NUTRITION
4.6
•120 ct$0.29/ct
$34.95 total
S
Sports Research
4.7
•90 ct$0.31/ct
$27.95 total