CoQ10

Evening with food

Coenzyme Q10 is a fat-soluble compound produced naturally in every cell of the body, where it plays a critical role in mitochondrial energy production. Found in highest concentrations in energy-demanding organs like the heart, liver, and kidneys, endogenous CoQ10 levels decline significantly with age and with statin use. It exists in two forms — ubiquinone (oxidized) and ubiquinol (reduced) — both widely available as supplements.

Rhonda PatrickTakes it

Research Evidence

May support blood pressure reduction in hypertensive individuals

Moderate

Offsets CoQ10 depletion caused by statin medications

Strong

May improve exercise performance and reduce fatigue

Limited

Provides antioxidant protection against lipid peroxidation

Moderate

Supports cardiovascular function and may improve heart failure symptoms

Strong

Reduces frequency of migraine headaches

Moderate

Source: Examine.com

Expert Evidence

10 references from 4 experts

“I also take my ubiquinol in the evening.”

Rhonda Patrick's EXACT Supplement Routine (doses, timing, & brands revealed)

1:43

Safety & Cautions

Side Effects

Mild nausea
Digestive discomfort
Insomnia if taken late in the day
Decreased appetite

CoQ10 is generally well-tolerated even at higher doses. Those on blood-thinning medications (especially warfarin) should consult a healthcare provider, as CoQ10 may reduce anticoagulant efficacy.

Pairs Well With

Omega-3 Fatty Acids (EPA)Magnesium Alpha Lipoic Acid Vitamin D3

Price Comparison

From $0.17/ct

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ZEBORABest Value

4.6

•120 ct

$0.17/ct

$20.99 total

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