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    Essential supplements for beginners

    New to supplements? These are the foundational supplements that multiple experts agree on. Each one below is taken by at least 2 of the 4 experts we track.

    This is SuppStacker's recommendation based on expert consensus—not an endorsement from any individual expert.

    4 of 4
    Expert Evidence
    AI-generated summary

    Brad Stanfield is a strong advocate for creatine, calling it the most effective nutritional supplement available for athletes and recommending it for virtually everyone except those with severe kidney disease. He emphasizes its well-established benefits for muscle performance and recovery, its emerging cognitive benefits (especially for older adults and females), and its reassuring safety profile with up to five years of data showing no adverse health risks including no evidence of hair loss.

    Brad Stanfield·Currently takes26 episodes

    “I think virtually everyone should be taking creatine outside of people who have got severe kidney disease because creatine seems to be fantastic for not only muscle recovery but also muscle performance in combination with exercise.”

    55:32
    Andy Galpin·Currently takes9 episodes

    “Me personally, based on the work that I've read, I think 5 to 10 grams per day is probably plenty for most people as a prophylactic. That said, this is what I do for my athletes: seven days or so prior to a high-risk situation, a competition, we up that dose to 20 to 30 grams for those seven days.”

    43:08
    Andrew Huberman·Currently takes15 episodes

    “I certainly feel better when I'm taking five grams of creatine monohydrate per day. I take it for the brain effects, and also because I like to think that it gives me a little bit of a DHT bump that I can actually see in my blood charts.”

    52:07
    Rhonda Patrick·Currently takes5 episodes

    “I take 5 to 10 grams of creatine per day. Most of the time I'm taking 10 grams and some days I take 15 to 20 on days that I'm traveling or don't get enough sleep. I find that doubling my dose up to about 20 grams really helps with cognitive function during lack of sleep.”

    5:20
    Price Comparison
    From $0.07/ct
    N
    NutricostBest Value
    4.6
    500 ct

    $0.07/ct

    Buy
    L
    Life Extension
    4.5
    120 ct

    $0.08/ct

    Buy
    N
    NOW Foods Creatine Monohydrate 1kg
    4.4
    200 ct

    $0.19/ct

    Buy
    View all 7 brands

    Electrolytes

    4 of 4
    Expert Evidence
    AI-generated summary

    Huberman drinks an electrolyte drink (Element, in which he's an investor) daily and adds salt to water each morning, crediting it with resolving shakiness he initially mistook for blood sugar issues. He emphasizes that sodium, potassium, and magnesium are critical for neuronal function, movement control, and mental clarity. No specific dosing numbers, cycling protocols, or cautions are discussed.

    Andrew Huberman·Currently takes3 episodes

    “It is extremely important to continue to ingest plenty of fluids and electrolytes. The neurons of your brain and body that control your movements, your thoughts, clarity of thinking in general, is critically dependent on the presence of adequate levels of sodium, potassium, and magnesium.”

    2:06
    Brad Stanfield·Currently takes3 episodes

    “Potassium helps to lower our blood pressure. It balances out our sodium levels while encouraging the walls of our blood vessels to relax. Its powerful effects is one of the reasons why I include it in my microvitamin.”

    8:58
    Andy Galpin·Currently takes1 episode

    “Most people on average eat around 1 to 2 grams of potassium a day where the need is probably more like 5 to 6 grams. It is a significantly underconsumed nutrient. This is why I actually like supplements or electrolytes that come with decent amounts of potassium.”

    54:55
    Rhonda Patrick·Currently takes1 episode

    “When I sauna, when I'm physically active, I also drink electrolytes after that. You can have an electrolyte drink that replaces some of the lost sodium, magnesium, and potassium.”

    13:48
    Price Comparison
    From $0.72/ct
    D
    Drip DropBest Value
    4.5
    32 ct

    $0.72/ct

    Buy
    L
    LMNT
    4.6
    30 ct

    $1.50/ct

    Buy
    L
    Liquid IV
    4.6
    16 ct

    $1.56/ct

    Buy

    Omega-3 Fatty Acids (EPA)

    4 of 4
    Expert Evidence
    AI-generated summary

    Brad Stanfield consistently takes omega-3 for heart attack risk reduction based on the VITAL trial and Mayo Clinic meta-analysis, but explicitly warns against high doses due to atrial fibrillation risk and notes no cognitive benefits from supplementation. He has not discussed specific timing or best practices beyond keeping the dose at around 1 gram.

    Brad Stanfield·Currently takes21 episodes

    “Personally, I take 1 gram a day. I think the evidence of a protective effect for heart health with omega-3 is quite compelling, but I want to stay away from higher doses that are linked to elevated risks of atrial fibrillation.”

    6:32
    Andrew Huberman·Currently takes19 episodes

    “There are now so many data on the valuable role of these essential EPA fatty acids, thresholds being somewhere between one and two grams per day of the EPA. So much so that there are now prescription forms of EPA that doctors are starting to prescribe for people with TBI. It also functions as an antidepressant equally good in clinical trials to SSRIs once one gets over basically two grams per day of the EPA.”

    6:32
    Andy Galpin·Currently takes7 episodes

    “DHA is accumulated in the brain, in fact it's about 10% of your brain or so. It's critical for everything from neurological function to injury risk, metabolic rate, prevention of neurodegeneration, aging and brain health, and Alzheimer's dementia.”

    54:31
    Rhonda Patrick·Currently takes18 episodes

    “...80 to 90% of the population is deficient in omega-3. You can essentially increase someone's life expectancy by 5 years by bringing them from a low omega-3 index of 4% to a high index of 8%. Supplementing with fish oil about two grams a day will get most people from a low index to a high omega-3 index.”

    1:15:12
    Price Comparison
    From $0.08/ct
    N
    NOW FoodsBest Value
    4.7
    180 ct

    $0.08/ct

    Buy
    N
    Nutricost
    4.7
    240 ct

    $0.12/ct

    Buy
    N
    NatureWise
    4.6
    60 ct

    $0.17/ct

    Buy
    View all 7 brands

    Multivitamin

    3 of 4
    Expert Evidence
    AI-generated summary

    Brad Stanfield actively takes and designed his own low-dose multivitamin (MicroVitamin), primarily motivated by the COSMOS study findings showing cognitive benefits equivalent to ~2 years less brain aging. He emphasizes multivitamins should complement—not replace—a healthy diet, and warns against mega-dosing. No cautions, reasons to stop, or recommendations against use were discussed.

    Brad Stanfield·Currently takes15 episodes

    “For me, I also take Micro Vitamin which is the low-dose multivitamin and mineral that I designed and personally use. I designed it to make sure that we don't mega-dose. Most multivitamins on the market mega-dose these micronutrients, which is not ideal. We want to hit our recommended daily intakes but we don't want to exceed them too much because we can cause side effects.”

    6:53
    Rhonda Patrick·Currently takes2 episodes

    “I'm taking the One multivitamin by Pure Encapsulations.”

    0:34
    Andrew Huberman·Currently takes1 episode

    “I take a multivitamin with my first meal of the day just to cover any basis that I might be missing out on.”

    9:11
    Andy Galpin·Discusses2 episodes

    “In our experience, if homocysteine is above 9 to 10 we're looking very seriously at other things. You'd be surprised how many have an omega-3 index under 5. This is why you see in those folks a little bit of basic multivitamin and omega-3 support and all of a sudden the brain fog is gone, the decline just disappears from these people really quickly.”

    30:06
    Price Comparison
    From $0.12/ct
    N
    NutricostBest Value
    4.6
    120 ct

    $0.12/ct

    Buy
    L
    Life Extension
    4.5
    120 ct

    $0.16/ct

    Buy
    N
    NOW Foods
    4.5
    90 ct

    $0.19/ct

    Buy
    View all 5 brands
    3 of 4
    Expert Evidence
    AI-generated summary

    Rhonda Patrick personally takes 1,000mg/day of nicotinamide riboside (Tru Niagen) and cites its ability to raise NAD levels and lower inflammation, though she has noted that even high doses of NR and NMN failed to raise NAD levels outside the liver in some research.

    Rhonda Patrick·Currently takes3 episodes

    “The tried and true function of nicotinamide riboside, at least something we can mostly expect if someone's going to supplement with the right dose being 500 milligrams to 1,000 milligrams, is lowering inflammation, particularly if you have a higher inflammatory status to start with.”

    1:05:10
    Brad Stanfield·Currently takes3 episodes

    “There's a couple of supplements that I used to take that I don't anymore. I stopped taking basis. It had nothing to do with any kind of deleterious side effects or any new information that came out, it was more that I thought about it and thought about whether we have enough human data.”

    30:34
    Andrew Huberman·Currently takes1 episode

    “I do indeed take an NR supplement every day. I take 500 milligrams of NR.”

    8:37
    Price Comparison
    From $0.21/ct
    U
    UNcenaBest Value
    4.5
    120 ct

    $0.21/ct

    Buy
    DORADO NUTRITION logo
    DORADO NUTRITION
    4.5
    30 ct

    $0.23/ct

    Buy
    partiQlar logo
    partiQlar
    4.3
    60 ct

    $0.75/ct

    Buy
    View all 6 brands

    Vitamin D3

    3 of 4
    Expert Evidence
    AI-generated summary

    Brad Stanfield consistently supplements with vitamin D3 at 1,000-2,000 IU daily (via his MicroVitamin product) to prevent deficiency, while strongly cautioning against high doses (4,000+ IU), which he notes can reduce bone density and cause toxicity. He acknowledges vitamin D does not reduce cancer or cardiovascular disease risk but values it for calcium absorption, bone health, and potential autoimmune and telomere benefits.

    Brad Stanfield·Currently takes16 episodes

    “Personally, I take 1,000 international units of vitamin D as part of MicroVitamin. That level helps me make sure I'm locking in the benefits of vitamin D without getting anywhere near the high doses that might lead to problems.”

    9:48
    Rhonda Patrick·Currently takes11 episodes

    “The sweet spot for vitamin D is between 40 to 60 nanograms per milliliter for the lowest all-cause mortality. I take 4,000 IU of vitamin D a day because that is the tolerable upper intake and it is quite safe.”

    9:56
    Andrew Huberman·Currently takes3 episodes

    “I think most physicians would agree that supplementing with anywhere from 1,000 to 2,000 IU of vitamin D per day is probably safe for most people and will buffer that level of vitamin D in their system such that they're unlikely to be deficient.”

    1:47:13
    Andy Galpin·Discusses4 episodes

    “If you don't have enough vitamin D, you'll get about a quarter of the calcium absorption through your gut that you would if vitamin D is sufficient. Your bone cells actually directly have vitamin D receptors on them, so there's a direct action there as well.”

    12:54
    Price Comparison
    From $0.03/ct
    Nature Made logo
    Nature MadeBest Value
    4.8
    300 ct

    $0.03/ct

    Buy
    N
    NatureWise
    4.7
    360 ct

    $0.04/ct

    Buy
    N
    Nutricost
    4.8
    240 ct

    $0.04/ct

    Buy
    View all 6 brands

    Vitamin K2

    3 of 4
    Expert Evidence
    AI-generated summary

    Brad Stanfield takes vitamin K2 daily for bone strength and dental health, though he acknowledges mixed evidence — notably that K2 plus vitamin D failed to reduce aortic valve calcification in a 2-year trial. He has no cautions about general use and no reports of stopping.

    Brad Stanfield·Currently takes8 episodes

    “Personally, I will still be using vitamin K2 supplements. I use the MK7 version and I take around 120 micrograms every day. I do this because there is some data to suggest that it helps to strengthen the bones and it may help reduce the calcium buildup in the blood vessels around the heart.”

    8:28
    Rhonda Patrick·Currently takes3 episodes

    “I personally do take vitamin K2 and I take around 50 micrograms a day. There have been some studies showing that taking between 25 and 50 micrograms a day of vitamin K2 does decrease calcium buildup in the arteries.”

    46:55
    Andrew Huberman·Currently takes2 episodes

    “I supplement K2, which helps with calcium metabolism.”

    1:35:24
    Price Comparison
    From $0.04/ct
    Carlyle logo
    CarlyleBest Value
    4.7
    240 ct

    $0.04/ct

    Buy
    N
    Nutricost
    4.7
    240 ct

    $0.06/ct

    Buy
    N
    NOW Foods
    4.7
    120 ct

    $0.13/ct

    Buy
    View all 6 brands

    Zinc

    3 of 4
    Expert Evidence
    AI-generated summary

    Huberman personally takes zinc daily and recommends it for testosterone support and immune function. He cites specific dosing thresholds for different goals. No cautions or concerns about zinc supplementation were discussed.

    Andrew Huberman·Currently takes5 episodes

    “I take 100 milligrams of zinc with that meal. I do that consistently.”

    9:25
    Rhonda Patrick·Currently takes2 episodes

    “I do the zinc lozenges by Life Extension. I suck on those and I'm probably taking between 80 milligrams to 100 milligrams a day, and that's only during exposure or very subtle onset of viral illness.”

    1:53
    Brad Stanfield·Currently takes1 episode

    “I take a supplement that's got 20 mg of zinc, but if you have a look at the elemental zinc, it's only 8.4 mg. The rest of the zinc I plan to get from my diet. The strategy is called micro-dosing — essentially making sure I'm hitting my recommended daily intake for zinc without mega-dosing.”

    5:01
    Andy Galpin·Discusses2 episodes

    “Up to 25% of endurance athletes have low or insufficient zinc status. It's involved in a lot of things that you would care about like protein synthesis, cell function, glucose regulation, endocrine function, immunity, healing, and so on. So you really want to pay attention to overall zinc status.”

    46:45
    Price Comparison
    From $0.05/ct
    N
    NOW FoodsBest Value
    4.7
    250 ct

    $0.05/ct

    Buy
    N
    Nutricost
    4.7
    240 ct

    $0.07/ct

    Buy
    L
    Life Extension
    4.7
    90 ct

    $0.08/ct

    Buy
    View all 6 brands

    Magnesium

    2 of 4
    Evening, 30-60 min before bed
    Expert Evidence
    AI-generated summary

    Huberman is a strong advocate for magnesium, distinguishing between forms for different purposes: magnesium threonate (or bisglycinate) for sleep, and magnesium malate for reducing muscle soreness and inflammation. He has no cautions beyond minor tolerability issues, and has not discussed stopping or recommending against magnesium.

    Andrew Huberman·Currently takes8 episodes

    “Magnesium has been shown to increase the depth of sleep and has been shown to decrease the amount of time that it takes to fall asleep. Magnesium threonate seems to be the more bioavailable form of magnesium and is shuttled preferentially to the brain, which is where you want it.”

    1:36:48
    Brad Stanfield·Currently takes6 episodes

    “Magnesium taurate is rapidly absorbed and it can get into the brain, so that's the form that I take. I take 125 milligrams of elemental magnesium. I do not advocate for mega dosing.”

    3:02
    Andy Galpin·Discusses1 episode

    “There are all kinds of forms like magnesium threonate, bisglycinate, and malate. Right now I don't know of any compelling evidence to suggest one of those forms is any better than another. Magnesium threonate has become more popular recently and that may turn out to be more effective, but there's just not enough data for us to have an answer at this point.”

    1:16:14
    Price Comparison
    From $0.08/ct
    N
    NatureBell
    4.7
    240 ct

    $0.08/ct

    Buy
    N
    NutricostBest Value
    4.7
    180 ct

    $0.08/ct

    Buy
    D
    Double Wood Supplements
    4.6
    180 ct

    $0.09/ct

    Buy
    View all 17 brands

    Probiotics

    2 of 4
    With meals
    Expert Evidence
    AI-generated summary

    Huberman takes probiotics and believes in their value, noting the gut microbiome communicates with the brain and can influence mood through neurotransmitter pathways. However, he cautions that excessive intake of certain strains like lactobacillus can cause brain fog. No specific brand, dosage, or timing guidance is provided.

    Andrew Huberman·Currently takes2 episodes

    “I do believe in probiotics. I take probiotics. But there are studies that show that if you take lots and lots of certain probiotics like lactobacillus and you really ramp up the levels, there are things like brain fog that can come from that.”

    23:11
    Rhonda Patrick·Currently takes1 episode

    “VSL#3 is the probiotic that I take. The sachets have 450 billion, which is more than what the capsules have. 450 billion is like 10 times more than what most probiotics have.”

    44:15
    Price Comparison
    From $0.48/ct
    L
    Life ExtensionBest Value
    4.5
    60 ct

    $0.48/ct

    Buy
    J
    Jarrow Formulas
    4.5
    30 ct

    $0.83/ct

    Buy

    What's next?

    Once you've established a foundation, explore individual expert stacks to see what else they take for specific goals like sleep, focus, or longevity.