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    Aspirin

    With food

    Aspirin (acetylsalicylic acid) is one of the oldest and most widely used medications, originally derived from willow bark. It belongs to the NSAID class and is used at various doses for pain relief, fever reduction, anti-inflammatory effects, and cardiovascular protection.

    Andrew Huberman
    Andrew HubermanTakes it
    Brad Stanfield
    Brad StanfieldStopped
    Research Evidence
    Effective for short-term pain and fever relief
    Strong
    Anti-inflammatory effects may benefit chronic inflammatory conditions
    Moderate
    May have protective effects against certain other cancers
    Limited
    Does not provide clear benefit for primary cardiovascular prevention in healthy adults
    Strong
    May reduce risk of colorectal cancer with long-term use
    Moderate
    Reduces risk of recurrent heart attack and stroke in those with established cardiovascular disease
    Strong
    Source: Examine.com

    Expert Evidence

    23 references from 2 experts

    “I personally like to avoid taking painkillers unless I have to take them. I might take an aspirin every once in a while, but I really like to avoid taking painkillers.”

    Protocols to Strengthen & Pain Proof Your Back

    1:12:48
    Safety & Cautions

    Side Effects

    • Gastrointestinal bleeding and ulcers
    • Increased bruising and bleeding tendency
    • Stomach pain and nausea
    • Tinnitus at high doses
    • Allergic reactions in aspirin-sensitive individuals
    Aspirin carries meaningful bleeding risks including gastrointestinal and intracranial hemorrhage, especially with long-term use. It should only be taken regularly under medical guidance, and is contraindicated in children with viral illness due to the risk of Reye's syndrome.
    Pairs Well With
    Omega-3 Fatty Acids (EPA)Vitamin D3