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    Aspirin

    With food

    Aspirin (acetylsalicylic acid) is one of the oldest and most widely used medications, originally derived from willow bark. It belongs to the NSAID class and is used at various doses for pain relief, fever reduction, anti-inflammatory effects, and cardiovascular protection.

    Research Evidence
    Effective for short-term pain and fever relief
    Strong
    Anti-inflammatory effects may benefit chronic inflammatory conditions
    Moderate
    May have protective effects against certain other cancers
    Limited
    Does not provide clear benefit for primary cardiovascular prevention in healthy adults
    Strong
    May reduce risk of colorectal cancer with long-term use
    Moderate
    Reduces risk of recurrent heart attack and stroke in those with established cardiovascular disease
    Strong
    Source: Examine.com

    Expert Evidence

    2 references from 1 expert

    Recommends against

    “For people who have never had a heart attack or stroke, aspirin didn't appear to protect against your first heart attack or stroke. Aspirin significantly increases the chances of major bleeding including brain bleeding, so using aspirin to try and prevent your first heart attack is generally not a good idea.”

    Aspirin Alert: The Hidden Risks Revealed

    0:02
    Brad Stanfield

    2 references in 2 episodes from 2021–2023

    AI-generated summary

    Brad Stanfield recommends against aspirin, stating he doesn't take it himself due to lack of clear benefit and increased serious risks. He cites evidence that aspirin doesn't protect against a first heart attack or stroke in primary prevention and significantly increases the chances of major bleeding including brain bleeding. No dosing guidance or specific conditions where he would recommend it are discussed.

    2023
    2021
    Safety & Cautions

    Side Effects

    • Gastrointestinal bleeding and ulcers
    • Increased bruising and bleeding tendency
    • Stomach pain and nausea
    • Tinnitus at high doses
    • Allergic reactions in aspirin-sensitive individuals
    Aspirin carries meaningful bleeding risks including gastrointestinal and intracranial hemorrhage, especially with long-term use. It should only be taken regularly under medical guidance, and is contraindicated in children with viral illness due to the risk of Reye's syndrome.
    Pairs Well With
    Omega-3 Fatty Acids (EPA)Vitamin D3
    Price Comparison
    From $0.05/ct
    B
    BayerBest Value
    4.8
    •200 ct

    $0.05/ct

    $9.47 total

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