Pterostilbene
Pterostilbene is a naturally occurring polyphenol found predominantly in blueberries, grapes, and certain tree barks. It is a methylated derivative of resveratrol with significantly improved oral bioavailability due to its two methoxy groups, which enhance lipophilicity and metabolic stability. It has attracted research interest for its antioxidant, anti-inflammatory, and neuroprotective properties.
Expert Evidence
1 reference from 1 expert

“Blueberries contain pterostilbene which is chemically similar to resveratrol and has been shown to lower triglycerides and blood glucose levels in mice. Pterostilbene has also been shown to be more potent than resveratrol in improving cognitive function.”
Smoothie #2: Prebiotics, Phytochemicals, "Anti-Nutrients" & Hydrolyzed Collagen
8:511 reference in 1 episode from 2016
Rhonda Patrick highlights pterostilbene as a compound found in blueberries that is chemically similar to resveratrol but more potent for cognitive function. She cites mouse studies showing it lowers triglycerides and blood glucose. No evidence of personal use, no dosing recommendations, and no cautions discussed.
Side Effects
- Mild increase in LDL cholesterol at higher doses
- Gastrointestinal discomfort
- Headache
$0.12/ct
$24.95 total
$0.33/ct
$19.95 total
$0.33/ct
$19.95 total
$0.37/ct
$21.95 total
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$22.00 total
$0.49/ct
$29.15 total