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    Arginine

    30-60 minutes before exercise

    Arginine is a semi-essential amino acid naturally found in meat, fish, dairy, and nuts. It serves as the primary substrate for nitric oxide synthase, the enzyme responsible for producing nitric oxide in blood vessels. Arginine is widely used to support cardiovascular health, exercise performance, and circulatory function.

    Research Evidence
    Supports healthy blood pressure in mildly hypertensive individuals
    Moderate
    Enhances exercise blood flow and nutrient delivery to muscles
    Moderate
    Supports wound healing and immune function
    Moderate
    Increases nitric oxide production and improves vascular function
    Strong
    May improve exercise endurance and reduce fatigue
    Limited
    Source: Examine.com

    Expert Evidence

    12 references from 2 experts

    “Arginine can increase growth hormone levels substantially. Taking arginine can dramatically increase growth hormone release 400 to 600% above baseline.”

    How to Control Your Metabolism by Thyroid & Growth Hormone | Huberman Lab Essentials

    19:30
    Safety & Cautions

    Side Effects

    • Gastrointestinal discomfort at high doses
    • Diarrhea
    • Bloating
    • Low blood pressure in sensitive individuals
    Arginine is generally well-tolerated at standard doses. Those taking blood pressure medications or nitrates should consult a healthcare provider before supplementing, as arginine may amplify blood pressure-lowering effects.
    Pairs Well With
    CitrullineOmega-3 Fatty Acids (EPA)CoQ10
    Price Comparison
    From $0.21/ct
    N
    NOW FoodsBest Value
    4.6
    •120 ct

    $0.21/ct

    $24.63 total

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