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    Saffron

    Morning

    Saffron is a spice harvested from the stigmas of the Crocus sativus flower, native to Southwest Asia and widely cultivated in Iran. It has been used in traditional medicine for centuries and has gained attention in modern research for its mood-supporting and anxiolytic properties. The active compounds crocin and safranal are believed to be responsible for most of its therapeutic effects.

    Research Evidence
    May support appetite regulation
    Limited
    May lower anxiety scores on standardized rating scales
    Moderate
    May have antioxidant and neuroprotective properties
    Limited
    May reduce symptoms of mild to moderate low mood
    Strong
    May support healthy stress response
    Moderate
    Source: Examine.com

    Expert Evidence

    3 references from 1 expert

    “There are 12 studies showing that orally ingested saffron is effective for reducing anxiety on standard inventories like the Hamilton Anxiety Rating Scale.”

    Erasing Fears & Traumas Using Modern Neuroscience | Huberman Lab Essentials

    32:10
    2025
    2021
    Safety & Cautions

    Side Effects

    • Dry mouth
    • Drowsiness
    • Nausea at higher doses
    • Headache
    • Appetite changes
    At standard supplemental doses of 30 mg per day, saffron is generally well-tolerated with a mild side-effect profile. Pregnant women should avoid supplemental doses, as high amounts have historically been associated with uterine stimulation.
    Pairs Well With
    MagnesiumOmega-3 Fatty Acids (EPA)Vitamin D3L-Theanine