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    Cannabidiol (CBD)

    Evening or before bed

    Cannabidiol (CBD) is a non-intoxicating compound derived from the Cannabis sativa plant. Unlike THC, it does not produce a euphoric high, making it one of the most widely studied cannabinoids for therapeutic applications. CBD is available in oils, capsules, gummies, and topical formulations, and has gained significant attention for its potential effects on anxiety, pain, and neurological conditions.

    Research Evidence
    May reduce symptoms of generalized and social anxiety
    Moderate
    May improve sleep quality and onset latency
    Moderate
    Potential neuroprotective effects in neurodegenerative conditions
    Limited
    May reduce chronic inflammatory and neuropathic pain
    Limited
    Reduces seizure frequency in treatment-resistant epilepsy
    Strong
    Source: Examine.com

    Expert Evidence

    7 references from 2 experts

    “Avoiding cannabis use and maybe even CBD use within 8 to 12 hours of sleep can be very beneficial if your goal is to improve the quality of your sleep.”

    AMA #2: Improve Sleep, Reduce Sugar Cravings, Optimal Protein Intake, Stretching Frequency & More

    8:32
    Safety & Cautions

    Side Effects

    • Drowsiness or fatigue
    • Diarrhea
    • Changes in appetite
    • Dry mouth
    • Potential liver enzyme elevations at high doses
    CBD can interact with several medications by inhibiting cytochrome P450 enzymes (particularly CYP3A4 and CYP2C19), so individuals taking prescription drugs—especially blood thinners, anti-epileptics, or immunosuppressants—should consult a healthcare provider before use. It is generally well-tolerated at moderate doses in most adults.
    Pairs Well With
    MagnesiumL-TheanineOmega-3 Fatty Acids (EPA)AshwagandhaMelatonin