Glutathione
Glutathione is a tripeptide composed of glutamate, cysteine, and glycine that is synthesized in virtually every cell of the body. Often referred to as the master antioxidant, it plays a critical role in neutralizing reactive oxygen species, recycling other antioxidants like vitamins C and E, and supporting phase II liver detoxification. Oral supplementation has historically faced bioavailability challenges, leading to the development of liposomal and acetylated forms.
Expert Evidence
1 reference from 1 expert
“Liposomal glutathione can be incredibly dangerous. Since the liposomal glutathione can bypass the body's normal processes, the body can't regulate it and that can mean toxic levels of glutathione in our cells.”
NAC (& Glutathione) Crucial New Research
2:011 reference in 1 episode from 2021
Brad Stanfield recommends against liposomal glutathione, warning it can be "incredibly dangerous" because it bypasses the body's normal regulatory processes, potentially leading to toxic cellular levels. No personal use, dosing guidance, or benefits are discussed — his position is purely cautionary.
Side Effects
- Bloating or digestive discomfort at higher doses
- Potential cramping with oral forms
- Allergic reactions in rare cases
- Concern about excessive cellular levels with liposomal forms bypassing normal regulation
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