NMN

Currently takes

“I confess I take NMN powder. I don't get paid to say this. I don't have any belief that it's going to increase my lifespan, but it seems to have a pro-energy effect that I like.”

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

33:45

3 references in 3 episodes from 2023–2024

Huberman takes 1-2 grams of sublingual NMN powder daily, reporting subjective increases in energy, faster hair growth, and faster nail growth. He explicitly states he has no belief it will increase lifespan but values the pro-energy effect. All three references are personal consumption reports with no controlled evidence cited, no cautions discussed, and no dosing rationale beyond self-experimentation.

Previously took

“I also used to take NMN, quercetin, and fisetin, all of which I've stopped because the current research suggests that there's no added benefit beyond a placebo. I don't warn against those supplements though because the safety data is reassuring so far.”

Why Many People Are Abandoning Intermittent Fasting

10:05

3 references in 3 episodes from 2022–2024

Stanfield stopped taking NMN roughly two years ago after reviewing the research, concluding that human clinical trials of NAD precursors (NMN and NR) have consistently failed to show anti-aging benefits beyond placebo. He recommends against supplementing vitamin B3 in any form beyond 50 mg due to long-term safety concerns, though he notes NMN's short-term safety data is reassuring. No dosing guidance for NMN itself is provided.

Recommends against

“They gave mice that had pancreatic cancer nicotinamide mononucleotide and it accelerated tumor growth. If you already have a bunch of tumors and then you're giving a bunch of whether it's folate or NAD or something, you might expect rapid cancer growth.”

How To Boost NAD Levels To Fight Inflammation, Improve Recovery, and Slow Aging

1:28:06

1 reference in 1 episode

Rhonda Patrick raises concerns about NMN based on mouse research showing that nicotinamide mononucleotide accelerated tumor growth in mice with pancreatic cancer, suggesting that supplementing with NAD precursors could fuel rapid cancer growth in individuals with existing tumors. She does not report personal use of NMN, provide dosing guidance, or discuss any potential benefits.