PQQ (Pyrroloquinoline Quinone)
Pyrroloquinoline quinone (PQQ) is a redox cofactor naturally present in soil, interstellar dust, and small amounts in foods like natto, parsley, and green tea. It has gained attention for its potential to stimulate the creation of new mitochondria and protect existing ones from oxidative damage. PQQ is not classified as a vitamin but acts as a powerful antioxidant at the cellular level.
Expert Evidence
2 references from 1 expert
“I also take PQQ by Life Extension.”
This Is Everything Rhonda Patrick Supplements With
1:382 references in 2 episodes from 2024–2025
Rhonda Patrick takes PQQ daily, specifically the Life Extension brand, timing it with her afternoon lunch. She confirms personal use but provides no dosage details, specific benefits, or mechanistic rationale in these references.
Side Effects
- Headache at higher doses
- Mild fatigue or drowsiness
- Possible digestive discomfort