Apigenin
Apigenin is a naturally occurring flavonoid concentrated in chamomile tea, parsley, celery, and other plant foods. It has gained attention primarily as a sleep-supporting compound due to its calming effects on the nervous system. It is one of the most well-studied dietary flavonoids for its sedative and anxiolytic properties.
Research Evidence
May have neuroprotective properties
LimitedEnhances GABAergic neurotransmission
ModerateReduces mild anxiety and promotes relaxation
ModerateAnti-inflammatory effects in preclinical models
LimitedSupports faster sleep onset
ModerateExpert Evidence
21 references from 2 experts
Safety & Cautions
Side Effects
- Mild sedation or grogginess if taken during the day
- Possible digestive discomfort at high doses
- Rare allergic reactions in those sensitive to chamomile or related plants
Apigenin is generally well-tolerated at standard supplement doses and is considered safe for nightly use. Those with allergies to plants in the Asteraceae family (chamomile, ragweed) should exercise caution, and pregnant or nursing individuals should consult a healthcare provider before use.
Pairs Well With
Price Comparison
From $0.12/ct
D
Double Wood
4.5
•120 ct$0.14/ct
$16.96 total
N
NutricostBest Value
4.5
•180 ct$0.12/ct
$21.95 total
S
Swanson
4.5
•90 ct$0.24/ct
$21.99 total
N
Nootropics Depot
4.3
•60 ct$0.33/ct
$19.99 total