Andrew Huberman

Andrew Huberman on Apigenin

Reported use

14 episodes · 20 references · 2021–2025

Based on dated public statements, not confirmation of use today.

Andrew Huberman has reported taking Apigenin. Referenced across 14 episodes with 20 total references.

View full Apigenin page with research, safety, and pricing →
Consumption Evidence (5)
Reported useApigenin2:05:43

“I've had quite good results from taking something called apigenin. I think I take 50 milligrams about 30 minutes before sleep.”

The Science & Practice of Perfecting Your Sleep | Dr. Matt Walker

Reported useApigenin1:48:48

“I take 50 milligrams of apigenin in capsule form every night before I go to sleep. I've been doing that for well over eight years now.”

How to Control Your Cortisol & Overcome Burnout

Reported useApigenin2:07:08

“My existing toolkit for sleep... consists of magnesium threonate, apigenin, and theanine.”

The Science & Treatment of Obsessive Compulsive Disorder (OCD)

Reported useApigenin25:45

“I take it before bedtime 50 milligrams.”

Boost Your Energy & Immune System with Cortisol & Adrenaline | Huberman Lab Essentials

Reported useApigenin1:29:14

“I take it before bedtime, 50 milligrams.”

Using Cortisol & Adrenaline to Boost Our Energy & Immune System Function

Benefits (6)

“Apigenin increases some of the enzymes associated with GABA metabolism. GABA is an inhibitory neurotransmitter that shuts down the forebrain.”

Using Science to Optimize Sleep, Learning & Metabolism

“Magnesium threonate, apigenin, and theanine, which together can really enhance the speed at which one falls asleep and people's ability to stay asleep and to really get into those deep stages of sleep that are particularly restorative.”

Sleep Toolkit: Tools for Optimizing Sleep & Sleep-Wake Timing

“...50 milligrams of apigenin also can augment or support this kind of creation of a sleepiness to help fall asleep and stay asleep.”

Master Your Sleep & Be More Alert When Awake | Huberman Lab Essentials

“Apigenin acts as a little bit of a hypnotic by activating chloride channels and increasing GABA in the brain, basically making you feel a little sleepy.”

How to Defeat Jet Lag, Shift Work & Sleeplessness

“The major source of action is to calm the nervous system and it does that primarily by adjusting things like Gaba and chloride channels but also has a mild effect in reducing cortisol.”

Boost Your Energy & Immune System with Cortisol & Adrenaline | Huberman Lab Essentials

Best practices (6)
Best practiceApigenin1:14:36

“...50, 5-0, milligrams of apigenin. And again, you could just take the apigenin on its own.”

Sleep Toolkit: Tools for Optimizing Sleep & Sleep-Wake Timing

Best practiceApigenin27:53

“Apigenin is the substance that's found in chamomile and 50 milligrams of apigenin taken 30 minutes before sleep can act as another way to shut off the forebrain and reduce rumination, reduce anxiety and allow people to fall and stay asleep.”

Maximize Productivity, Physical & Mental Health With Daily Tools | Huberman Lab Essentials

Best practiceApigenin1:18:05

“...50 milligrams of apigenin also can augment or support this kind of creation of a sleepiness to help fall asleep and stay asleep.”

Master Your Sleep & Be More Alert When Awake

Best practiceApigenin52:51

“Apigenin, the chamomile extract, 50 milligrams of that seems to really accelerate the passage into sleep for a number of people.”

Andrew Huberman - TRT, PEDs, Maxing Out Natural T, Supplements, Diet, Sleep & Hormones Deep Dive

Best practiceApigenin27:01

“...50 milligrams of Apigenin can be very beneficial. You could just take the Apigenin on its own or in combination with the other supplements mentioned in this stack.”

Essentials: Sleep Toolkit for Optimizing Sleep & Sleep-Wake Timing

Cautions (3)

“Apigenin is a fairly potent estrogen inhibitor, so women who want to keep their estrogen levels high should probably avoid apigenin altogether.”

Master Your Sleep & Be More Alert When Awake

“Apigenin has anti-estrogenic effects, so if you want to keep your estrogen up, you might want to be cautious about it.”

How to Defeat Jet Lag, Shift Work & Sleeplessness

“Apigenin is a fairly potent estrogen inhibitor... women who want to keep their estrogen levels high should probably avoid apigenin altogether.”

Master Your Sleep & Be More Alert When Awake | Huberman Lab Essentials

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