GABA
GABA (gamma-aminobutyric acid) is the brain's main inhibitory neurotransmitter, responsible for calming neural activity throughout the central nervous system. It is produced naturally in the body from glutamate and is also available as a dietary supplement derived from fermentation processes. GABA supplements are primarily used to support relaxation, reduce stress, and improve sleep quality.
Research Evidence
Promotes relaxation and reduces subjective stress
ModerateImproves sleep quality and reduces time to fall asleep
ModerateMay increase growth hormone levels at high doses
LimitedSupports mood and emotional well-being
LimitedReduces anxiety symptoms in acute stress situations
ModerateSafety & Cautions
Side Effects
- Tingling or flushing sensation
- Mild drowsiness
- Temporary shortness of breath at high doses
- Digestive discomfort
GABA is generally well-tolerated at standard supplemental doses. However, individuals taking medications that affect GABA pathways (such as benzodiazepines, barbiturates, or other sedatives) should consult a healthcare provider before supplementing, as additive effects may occur.
Pairs Well With
Price Comparison
From $0.07/ct
N
NOW Foods
4.5
•100 ct$0.09/ct
$8.70 total
N
Nutricost
4.6
•240 ct$0.08/ct
$18.95 total
D
Double WoodBest Value
4.5
•300 ct$0.07/ct
$19.95 total
T
Thorne
4.5
•60 ct$0.57/ct
$34.00 total