Andrew Huberman

Andrew Huberman on Vitamin B6 (P-5-P)

Reported use

4 episodes · 7 references · 2021–2023

Based on dated public statements, not confirmation of use today.

Andrew Huberman has reported taking Vitamin B6 (P-5-P). Referenced across 4 episodes with 7 total references.

View full Vitamin B6 (P-5-P) page with research, safety, and pricing →
Consumption Evidence (1)

“After some major event, I would take a couple hundred milligrams of vitamin B6 to kind of offset some of that low.”

How to Increase Motivation & Drive

Benefits (4)

“B vitamins, in particular B6 or vitamin B6, can potently reduce prolactin levels. Prolactin and dopamine tend to work in kind of push-pull fashion.”

Optimize & Control Your Brain Chemistry to Improve Health & Performance | Huberman Lab Podcast #80

“Vitamin B6 is a fairly potent prolactin inhibitor. By way of inhibiting prolactin, it increases dopamine.”

How to Increase Motivation & Drive

“People have started to explore the use of things like P5P, which is essentially a metabolite of vitamin B6, which is known to suppress prolactin as a way to try and buffer some of that crash.”

The Science of MDMA & Its Therapeutic Uses: Benefits & Risks | Huberman Lab Podcast

“Some people take vitamin B6 in order to reduce prolactin levels and thereby reduce the duration of the refractory period.”

The Science of How to Optimize Testosterone & Estrogen

Cautions (2)

“For people who have diabetic neuropathy, you need to be careful with vitamin B6. I was told that it can in some cases exacerbate peripheral neuropathy.”

How to Increase Motivation & Drive

“You should be cautious about taking excessive levels of B6. There is evidence that having excessively high levels of B6 or supplementing with excessively high levels of B6 can cause some peripheral neuropathy.”

Optimize & Control Your Brain Chemistry to Improve Health & Performance | Huberman Lab Podcast #80

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