Rhonda Patrick on L-Theanine
1 episode · 3 references · 2025
- Patrick highlights L-theanine's synergy with caffeine, noting it increases GABA and glycine signaling, producing alpha brain waves linked to calm alertness without sedation. - She recommends 100–200 mg L-theanine paired with 100–150 mg caffeine to significantly improve cognitive performance. - Patrick notes L-theanine dampens caffeine's transient blood pressure spike without sacrificing alertness. No dosing for standalone use or specific supplement brands mentioned.
View full L-Theanine page with research, safety, and pricing →“L-theanine even dampens caffeine's transient blood pressure increase without sacrificing alertness.”
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“L-theanine works synergistically with caffeine. It increases GABA and glycine signaling in the brain creating a state of characterized alpha brain waves linked to calm, attentive states without sedation.”
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“Combining roughly 100 to 200 milligrams of L-theanine with about 100 to 150 mg of caffeine significantly improves cognitive performance.”
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