Gil Carvalho on Berberine

“Berberine is another one that's been shown in meta analyses to reduce spikes by 18 points, 18 mg per deciliter.”

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“A meta-analysis reported that berberine helped reduce the thickness of the artery wall, specifically looking at carotid arteries and ultrasound.”

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“A meta-analysis of 46 randomized control trials found that berberine helped reduce hemoglobin A1C when compared to a placebo, with an effect similar to metformin.”

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“Randomized trials and meta-analyses generally show that berberine can help lower cholesterol, fasting glucose, triglycerides, blood pressure, and body weight.”

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“Many of those supplements have been shown to reduce cholesterol levels. Some of them might even reduce the thickness to the size of the plaque in the arteries according to some studies.”

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“The amount of berberine used in these trials is between 0.3 and 1.8 grams a day, so in that ballpark of one gram a day plus or minus 0.7.”

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“Taking 500 milligrams of berberine twice a day, for a total of one gram, has been shown to lower Apo B by 10 to 15%.”

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“Some side effects have been reported, with GI distress being the most common, and it can interact with diabetes meds, potentially dropping glucose too low.”

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“There's been studies looking at the dosage of the substance in supplements and sometimes it mismatches what's advertised on the label by a massive margin.”

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“One exception is if you're pregnant or breastfeeding; berberine seems to cross the placenta and also ends up in breast milk, so it makes sense to be more cautious there.”

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“Between 5 and 14% of patients taking berberine report some side effects; they're usually mild, most common is gastrointestinal symptoms like nausea, diarrhea, constipation, gas, and stomach pain.”

Can Berberine shrink PLAQUE in your Arteries? | Fact-checked