Andrew Huberman on Fadogia Agrestis
7 episodes · 9 references · 2021–2025
- Huberman takes Fadogia Agrestis at 600mg/day cycled 8-12 weeks on, weeks off, to boost luteinizing hormone and testosterone - Primary mechanism is increasing luteinizing hormone, which raises both testosterone and estrogen levels - No best-practice or dosing-protocol references beyond his personal regimen; cautions about testicular toxicity at high doses in rodent studies
Consumption
- Takes 600mg per day, one-third of the recommended bottle dose - Cycles 8-12 weeks on, then a few weeks off - Reports long-term use with bloodwork confirming safety
Benefits
- Increases luteinizing hormone, which in turn raises testosterone and estrogen levels - Shown to increase testicular size and volume in studies - Acts on LH without triggering negative feedback loops
Cautions
- High doses in rodent studies caused testicular toxicity - Limited human research available to confirm long-term safety - Huberman cycles off periodically, suggesting caution about continuous use
“Fadogia Agrestis at 600 milligrams, which is actually one-third of what's recommended on the bottle.”
Andrew Huberman - TRT, PEDs, Maxing Out Natural T, Supplements, Diet, Sleep & Hormones Deep Dive
“I've been taking fadogia for some period of time. I've been taking 600 milligrams per day, but I've been cycling it for about 8 to 12 weeks on and then a few weeks off.”
Tools for Hormone Optimization in Males | Dr. Kyle Gillett
“I've used things like Fadogia for vitality for a long time. I continue to use these and my bloodwork says it's fine.”
Health Effects & Risks of Kratom, Opioids & Other Natural Occurring Medicines | Dr. Chris McCurdy
“The consistent effect seems to be an increase in luteinizing hormone. There's a noticeable effect on testicular size and volume.”
Exercise, Nutrition, Hormones for Vitality & Longevity | Dr. Peter Attia
“Fadogia Agrestis is an herb that increases the levels of what's called luteinizing hormone. It has been shown, albeit in a limited number of studies, to increase levels of luteinizing hormone and thereby levels of testosterone and estrogen.”
Maximizing Productivity, Physical & Mental Health with Daily Tools
“Fadogia Agrestis can increase levels of luteinizing hormone and thereby levels of testosterone or levels of estrogen.”
How to Optimize Testosterone & Estrogen | Huberman Lab Essentials
“Fadogia agrestis can increase levels of luteinizing hormone and thereby levels of testosterone or levels of estrogen.”
The Science of How to Optimize Testosterone & Estrogen
“Fadogia Agrestis seems to increase luteinizing hormone in a non-positive feedback or negative feedback type way.”
Andrew Huberman - TRT, PEDs, Maxing Out Natural T, Supplements, Diet, Sleep & Hormones Deep Dive
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