Brad Stanfield on Spermidine
2 episodes · 9 references · 2021–2022
- Stanfield views spermidine favorably for its autophagy-driven anti-aging, cardiovascular, and cancer-prevention benefits, citing dose-dependent mortality reductions in humans and 10% lifespan extension in mice. - He does not supplement with spermidine, stating it can be obtained from diet alone. - No dosing guidance, timing recommendations, or safety cautions were discussed.
Benefits
- Spermidine activates autophagy, which is required for its anti-aging effects; knocking out autophagy genes eliminates the longevity benefits. - Linked to dose-dependent reductions in overall, cardiovascular, and cancer-related death rates in humans, plus 10% lifespan extension and preserved heart function in mice. - Human trials show moderate memory enhancement and increased hair follicle growth over three months versus placebo.
Cautions
- Stanfield explicitly chose not to add spermidine to his supplement stack, saying dietary intake is sufficient. - No specific safety risks, side effects, or contraindications were discussed. - No populations or conditions were flagged as reasons to avoid supplementation.
“In single cells in the lab, spermidine activates a process called autophagy or the cell clearance process. By clearing away those damaged components, we can rebuild new ones.”
Why You Should STOP Buying Spermidine Supplements
“Nutritional spermidine intake, it's been linked to overall reductions in cardiovascular and cancer-related death rates in humans.”
Spermidine - Get It From Your Diet (not supplements)
“Giving spermidine as a supplement to mice, it stops the age-related decline in cardiovascular or heart function and it increases overall lifespan by 10%.”
Spermidine - Get It From Your Diet (not supplements)
“During a three-month trial, the supplemented group of spermidine, they showed an increased growth of hair follicles compared to the placebo.”
Spermidine - Get It From Your Diet (not supplements)
“In a previous safety trial that looked at spermidine in humans, they found a moderate enhancement of memory performance.”
Spermidine - Get It From Your Diet (not supplements)
“The great news is we can get it from our diet, so I won't be adding it to my supplement stack.”
Spermidine - Get It From Your Diet (not supplements)
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$27.96 total
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$24.97 total