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    Garlic Extract

    Garlic extract is derived from Allium sativum bulbs and standardized for allicin and other organosulfur compounds. It has been used medicinally for thousands of years across cultures and is one of the most extensively studied herbal supplements, particularly for cardiovascular health.

    Research Evidence
    Exhibits antimicrobial properties against various pathogens
    Moderate
    Modestly reduces total and LDL cholesterol
    Strong
    Supports immune function and reduces cold severity
    Moderate
    Reduces TMAO levels from choline-containing supplements
    Moderate
    Lowers blood pressure in hypertensive individuals
    Strong

    Expert Evidence

    6 references from 1 expert

    Currently takes

    “I take 600 milligrams of garlic in capsule form anytime I eat, and I do that for general cardiovascular function. I make it a point to always ingest a 600 milligram capsule of garlic anytime I take Alpha-GPC to offset increases in TMAO.”

    Focus Toolkit: Tools to Improve Your Focus & Concentration

    1:32:36
    Andrew Huberman

    6 references in 5 episodes from 2022–2023

    AI-generated summary

    Huberman takes 600mg of garlic daily primarily to offset TMAO increases from Alpha-GPC and L-carnitine, while also noting general cardiovascular benefits. He has not discussed cautions or reasons to avoid garlic supplementation.

    Consumption

    He takes 600mg of garlic in capsule form every time he eats, and specifically whenever he takes Alpha-GPC or L-carnitine, to keep TMAO levels in check.

    Best Practices

    Take 600mg of garlic (containing allicin) on the same day as Alpha-GPC or acetyl-L-carnitine to offset the TMAO increase those supplements can cause.

    2023
    2022
    Safety & Cautions

    Side Effects

    • Garlic breath and body odor
    • Heartburn or acid reflux
    • Nausea when taken on an empty stomach
    • Increased bleeding risk at very high doses
    Garlic is generally well-tolerated at standard doses. Those on blood-thinning medications should consult a physician, as garlic may enhance anticoagulant effects.
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