
Andrew Huberman on Leucine
3 episodes · 3 references · 2021–2025
- Huberman recommends 700–3,000 mg of leucine per meal to support muscle protein synthesis and hypertrophy via increased myosin production. - He highlights leucine's role in activating the mTOR pathway, which he describes as vital for cell and muscle growth. - Evidence focuses on dosing and mechanism; no mention of specific food sources, timing relative to training, or potential downsides of supplementation.
View full Leucine page with research, safety, and pricing →“It has been shown that the amino acid leucine is vital for the cell growth process, including muscle growth, because of its relationship to the so-called mTOR pathway.”
Healthy Eating & Eating Disorders - Anorexia, Bulimia, Binging
“Ingesting 700 to 3,000 milligrams of the essential amino acid leucine with each meal is important. This is one of the best ways that's been shown to support the synthesis of more myosin if your goal is hypertrophy.”
Science of Muscle Growth, Increasing Strength & Muscular Recovery




