
Brad Stanfield on Multivitamin
20 episodes · 26 references · 2023–2025
- Stanfield takes a daily multivitamin and mineral supplement based on the COSMOS study results showing cognitive benefits equivalent to 2 years less brain aging - He advocates for low-dose formulations to meet recommended daily intakes, not megadosing, and emphasizes supplements should complement a good diet - No specific brand, dose amounts, or timing guidance discussed; no stopped-taking or recommend-against evidence exists
Consumption
- Stanfield personally takes a daily multivitamin and mineral supplement, switching from individual vitamin/mineral supplements to a combined formulation - His decision was driven specifically by the COSMOS study results on brain performance and cognition - He chose the multivitamin route to ensure he meets recommended daily intakes of all B vitamins every day
Benefits
- The COSMOS Mind study (2,000+ participants, 3-year RCT) found statistically significant improvements in global cognition, memory, and executive function from daily multivitamin use - The cognitive benefit was equivalent to reducing brain aging by approximately 2 years compared to placebo - A separate trial of 573 people also found multivitamin supplements significantly improved cognition and memory
Best Practices
- Stanfield advocates for low-dose multivitamins to reach optimal daily intakes, not megadosing beyond recommended levels - Supplements should complement a great diet and regular exercise, not replace them - For healthy people eating well and taking a low-dose multivitamin, routine micronutrient blood testing is unnecessary
Cautions
- Stanfield warns against megadosing — many multivitamin products contain doses orders of magnitude above recommended daily intakes - No specific adverse effects or contraindications were discussed beyond the megadosing concern - No evidence of recommending against multivitamins for any specific population
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“The Cosmos Mind study found that a daily multivitamin and mineral relative to placebo resulted in statistically significant benefits on global cognition, memory, and executive function.”
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“In no way should this replace a great diet and regular exercise; instead, the supplement is there to provide a top-up to make sure you're reaching the recommended daily intakes.”
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“For otherwise healthy people who eat a good diet and are taking a low-dose multivitamin and mineral supplement, there's no advantage to routine testing.”
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“I'm not advocating for mega dosing; all I'm suggesting is a low-dose multivitamin to help patients reach their optimal daily intakes for all of the micronutrients.”
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