Rhonda Patrick on Magnesium
18 episodes · 56 references · 2013–2025
- Patrick is a strong magnesium advocate, calling herself a "magnesium junky" and emphasizing its role in DNA repair, mitochondrial function, and mortality reduction. - Cites a study of 47,000 men showing 40% lower all-cause mortality and 50% lower cancer mortality with highest magnesium levels. - No specific dosing guidance or form recommendations discussed; no best-practice references available.
Consumption
- Patrick describes herself as a "magnesium junky" who prioritizes magnesium intake. - Eats large amounts of chlorophyll-containing leafy greens because magnesium sits at the center of the chlorophyll molecule. - No specific supplement form, dose, or frequency mentioned.
Benefits
- Magnesium-dependent enzymes enable mitochondria to repair oxidative stress damage and maintain DNA polymerase accuracy. - Without adequate magnesium, polymerase enzymes make more sequence errors and lose ability to fix those errors. - Study of 47,000 men over 18 years linked highest magnesium levels to 40% lower all-cause mortality and 50% lower cancer mortality.
Cautions
- Low magnesium levels impair the body's ability to produce new mitochondria during exercise. - This compromises exercise performance and adaptation. - Suggests magnesium deficiency may undermine the core benefits of physical training.
“It's one of the many reasons I'm a magnesium junky and why I eat a ton of chlorophyll containing leafy greens because magnesium's right at the center of that chlorophyll molecule.”
DEBUNKED: 2/3rds of Cancer "Just Bad Luck"
“I'm taking at night magnesi om so that's a combination of a variety of different magnesiums I take that in addition to the Magnesium glycinate that I take.”
This Is Everything Rhonda Patrick Supplements With
“I make my morning smoothie every day which consists of kale, chard, and spinach, which is my source of magnesium.”
How Diet & Lifestyle Influence Aging & Brain Function [UCSF Healthy Heart Talk Oct. 2014]
“The other one I sometimes take at night is magnesium glycinate by Pure Encapsulations.”
The Science of Magnesium and Its Role in Aging and Disease
“Magnesium is required for over 300 different enzymes in the body, including those that are important for the production of ATP, which is the energetic currency of the cell.”
Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
“Your mitochondria have the ability to repair damage from oxidative stress using the same magnesium-dependent enzymes.”
Maximizing Your Mitochondria with Magnesium
“These DNA repair enzymes actually require magnesium as a co-factor to function. Without magnesium, these DNA repair enzymes do not work efficiently.”
Rhonda Patrick at Orthomolecular Medicine Congress in Bussum, Netherlands (Keynote Oct. 3rd, 2015)
“Magnesium is a cofactor for over 300 different enzymes in the body. It's important for the production and utilization of energy in the form of ATP, but it's also important for repairing DNA damage.”
How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick
“For optimal bioavailability of magnesium supplements, it's also generally more effective to take the total daily dose in divided smaller amounts rather than a single large dose.”
The Science of Magnesium and Its Role in Aging and Disease
“Requirements for magnesium depend on age and gender. It's somewhere like 400 milligrams a day for men and somewhere like 300 to 350 for women.”
How Micronutrients & Exercise Ameliorate Aging | Dr. Rhonda Patrick
“Magnesium glycinate's a really good bioavailability, has very good bioavailability, so does magnesium malate or magnesium citrate.”
How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick
“Making sure you have the proper levels of magnesium in your cells by eating kale and spinach on a daily basis is very very important.”
Understanding Cancer, part I
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