Dr. Stacy Sims: Should women take creatine? A physiology-based masterclass for midlife hormones
17 references · Jan 31, 2026
“It's an illusion that people should only take creatine on days that they're working out.”
“It improves the capacity to be more stress resilient. Creatine helps maintain the integrity of our intestinal cells.”
“There are randomized control trials looking at mood disorder, depression, anxiety, and that it's lessened when you're using creatine.”
“If we are doing smaller doses, so it's a 3 to five grams, there's no bloating or water weight gain, which is a concern a lot for women.”
“Vitamin D for sure. You need to start dosing on some vitamin D cuz winter's coming your way.”
“Omega-3 fatty acids because omega-3s all help with cellular components to reduce inflammation.”
“If you are dosing with creatine five grams twice a day, it improves the capacity to be more stress resilient.”
“Vitamin D3 is really important for things like osteoporosis prevention. We see it's important for muscle and immunity also really important for brain health.”
“For women, the dose is three to five grams only once a day without carbohydrate.”
“I tell women they should start with maybe one and a half grams for one week and then work up to three grams the next week and then on the third week you're starting to get that five gram dose.”
“We want creatine monohydrate... preferably of course Creapure because the way it's produced.”
“If you're looking at a cheaper version of creatine monohydrate, it comes as an acid wash... this is why we start to see a lot of bloating and stomach discomfort.”
“It doesn't have an acute effect. It takes about 3 weeks for the body to be saturated.”
“I'm talking about 3 to 5 g daily. You can take a teaspoon and stir in your coffee cuz it's just a very easy powder that's really mixable.”









